(1) Instituto de
Universidad Nacional de General San Martín,
1650, San Martín, Argentina.
(2) Max-Planck-Institut fur Biologie, Abteilung
Correnstrasse 38, D-72076, Tübingen, Germany.
(#) Fernán Agüero and Vanina Campo contributed equally to this
(&) Corresponding authors.
(§) Present address: Cellular Biochemistry and Biophysics, Memorial Sloan-Kettering Cancer Center, 1275 NY Ave., Box 251, New York, NY, 10021, USA.
(*) Present address: MRC Laboratory of Molecular Biology. PNAC Unit, Hills Road Cambridge CB2 2QH, Cambridge, United Kingdom.
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T. cruzi transialidase (TcTS) and the T. carassii TS-like (TcaTS) were aligned together using clustalw. The portion of the alignment shown includes the mature catalytic domain only. Identity between residues is indicated with stars (*), conservative changes are indicated with double dots (:), less conservative changes are indicated with a single dot (.). Boxes highlight the residues involved in the catalytic centre of the sialidases of known crystal structure. I, II, and III are conserved aspartic boxes. NA is a signature motif of the neuramindase (NA) superfamily.
Results of BLASTX analysis against protein databases. We have divided matches in two categories:
All sequences have been subjected to similarity searches
against different databases, and to testcode evaluation of
their coding potential. A summary of the results for each
sequence is available.
If you are looking for a specific clone (e.g. clone 02j2) use the form below: